What’s Involved in the Study?

  • The study involves clinic visits, blood draws, and lung function tests
  • Qualified participants take investigational inhaled insulin for 12 months or continue mealtime injectable insulin for 6 months and then switch to investigational inhaled insulin for 6 months
  • Investigational inhaled insulin provided at no cost
  • Participants asked to check their glucose level frequently using a study provided continuous glucose monitor (CGM)
  • Compensation available and a CGM provided throughout the study
Click here for more information

Study Locations

Use the interactive map below to see where the study is taking place by entering a zip code in the search field below.

  • The study involves clinic visits, blood draws, and lung function tests
  • Qualified participants will either take inhaled insulin for 12 months or continue mealtime injectable insulin for 6 months and then switch to inhaled insulin for 6 months
  • Inhaled insulin will be provided at no cost
  • Participants will be asked to check their glucose level frequently using a study provided continuous glucose monitor (CGM)
  • Compensation will be available and a CGM will be provided throughout the study.
Click here for more information

Resource

"Children Are Not Little Adults: The Importance of Pediatric Research” - JDRF and MannKind Corporation discuss the importance of pediatric type 1 diabetes (T1D) research from both the patient and clinician perspective.

Click here to read JDRF’s blog – “The Innovative Insulin Your Kids Can’t Use…Yet – JDRF provides a summary of the INHALE-1 trial".

Important Safety Information

  • Inhaled insulin is a man-made human insulin that is breathed-in through your lungs (inhaled) and is used to control high blood sugar in adults with diabetes mellitus. It is not approved for use in children.
  • Inhaled insulin can cause serious side effects, including sudden lung problems (bronchospasms). Do not use inhaled insulin if you have long-term (chronic) lung problems such as asthma or chronic obstructive pulmonary disease (COPD). Before starting inhaled insulin, your study doctor will give you a breathing test to check how your lungs are working.
  • Inhaled insulin is not for use in place of long-acting insulin. Inhaled insulin must be used with basal insulin in people who have type 1 diabetes mellitus.
  • Inhaled insulin is not for use to treat diabetic ketoacidosis.
  • It is not known if inhaled insulin is safe and effective for use in people who smoke. Inhaled insulin is not for use in people who smoke or have recently stopped smoking (less than 6 months).
  • INHALE-1 aims to look at how safe inhaled insulin is and how well it works in children ages 4-17 who have type 1 and insulin-requiring type 2 diabetes mellitus.